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Compound Detail

CHEMBL3962430

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CCCCc1cc(O)c(=O)[nH]n1

Basic Information

ChEMBL ID CHEMBL3962430
Phase Preclinical
Structure Type MOL
InChI Key PURIDFKRYZLIJI-UHFFFAOYSA-N
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

168.2
MW (Da)
0.82
ALogP
3
HBA
2
HBD
66.0
PSA (Ų)
0.70
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C8H12N2O2
MW 168.20
Aromatic Rings 1
Heavy Atoms 12
NP-Likeness -0.56

Activity Summary

IC50 3 meas. best 8.16

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
D-amino-acid oxidase
CHEMBL5485
IC50 8.16 8.07 6.9 3

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine