Compound Detail
CHEMBL3989909
LENIOLISIB PHOSPHATE 💊 Approved Drug
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💊 Approved Drug
CCC(=O)N1CC[C@H](Nc2ncnc3c2CN(c2cnc(OC)c(C(F)(F)F)c2)CC3)C1.O=P(O)(O)O
Basic Information
| ChEMBL ID | CHEMBL3989909 |
| Name | LENIOLISIB PHOSPHATE |
| Phase | Approved |
| Structure Type | MOL |
| InChI Key | XXEDEGOAYSGNPS-ZOWNYOTGSA-N |
| Therapeutic | ✓ Yes |
| Parent Compound | CHEMBL3643413 |
| Active Moiety | CHEMBL3643413 |
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
7
Known Names
3
Indications
1
Mechanisms
Molecular Properties
450.5
MW (Da)
2.88
ALogP
7
HBA
1
HBD
83.5
PSA (Ų)
0.75
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| First Approval | 2023 |
| Availability | Prescription |
| Chirality | Single Enantiomer |
Mechanism of Action
| Mechanism | Action Type | Target | Direct | Efficacy |
|---|---|---|---|---|
| PI3-kinase p110-delta subunit inhibitor | INHIBITOR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | ✓ | ✓ |
Indications
Primary Immunodeficiency Diseases Common Variable Immunodeficiency Sjogren's Syndrome
Data from ChEMBL 36 via Core Engine