Compound Detail
CHEMBL3989928
REZAFUNGIN ACETATE 💊 Approved Drug
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💊 Approved Drug
CC(=O)[O-].CCCCCOc1ccc(-c2ccc(-c3ccc(C(=O)N[C@H]4C[C@@H](O)[C@@H](OCC[N+](C)(C)C)NC(=O)[C@@H]5[C@@H](O)[C@@H](C)CN5C(=O)[C@H]([C@@H](C)O)NC(=O)[C@H]([C@H](O)[C@@H](O)c5ccc(O)cc5)NC(=O)[C@@H]5C[C@@H](O)CN5C(=O)[C@H]([C@@H](C)O)NC4=O)cc3)cc2)cc1
Basic Information
| ChEMBL ID | CHEMBL3989928 |
| Name | REZAFUNGIN ACETATE |
| Phase | Approved |
| Structure Type | MOL |
| InChI Key | MXMWJAPNUIKPGF-YOFVRWEXSA-N |
| Therapeutic | ✓ Yes |
| Parent Compound | CHEMBL3989945 |
| Active Moiety | CHEMBL3989945 |
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
8
Known Names
5
Indications
1
Mechanisms
Molecular Properties
1226.4
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| First Approval | 2023 |
| Availability | Prescription |
| Chirality | Single Enantiomer |
Mechanism of Action
| Mechanism | Action Type | Target | Direct | Efficacy |
|---|---|---|---|---|
| Candida inhibitor | INHIBITOR | Candida | ✓ | ✓ |
Indications
Candidemia Candidiasis Candidiasis, Invasive Pneumonia, Pneumocystis Mycoses
ATC Classification
J02AX08
rezafungin acetate
Level 1: ANTIINFECTIVES FOR SYSTEMIC USE
Level 2: ANTIMYCOTICS FOR SYSTEMIC USE
Data from ChEMBL 36 via Core Engine