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Compound Detail

CHEMBL405370

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Nc1noc2cccc(-c3ccc(NC(=O)c4ccccc4)cc3)c12
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL405370
Phase Preclinical
Structure Type MOL
InChI Key VLNXUZCOGPVFFS-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

329.4
MW (Da)
4.33
ALogP
4
HBA
2
HBD
81.2
PSA (Ų)
0.59
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C20H15N3O2
MW 329.36
Aromatic Rings 4
Heavy Atoms 25
NP-Likeness -0.96

Literature References

PubMed DOI Target Context # Activities
18260617 10.1021/jm701096v Vascular endothelial growth factor receptor 2 1
18260617 10.1021/jm701096v Mast/stem cell growth factor receptor Kit 1
18260617 10.1021/jm701096v Receptor-type tyrosine-protein kinase FLT3 1

Data from ChEMBL 36 via Core Engine