Compound Detail
CHEMBL4063249
TP-021n Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL4063249 |
| Name | TP-021n |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BZXKWTWZOMZUEU-UHFFFAOYSA-N |
0
Targets
3
Activities
1
Assay Types
0
PK Parameters
20
Publications
0
Known Names
Molecular Properties
284.7
MW (Da)
3.12
ALogP
3
HBA
3
HBD
84.5
PSA (Ų)
0.68
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas.
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.6019/CHEMBL4507304 | Tyrosine-protein kinase ABL1 | 15 |
| - | 10.6019/CHEMBL5674860 | Colon cancer organoid | 12 |
| - | 10.6019/CHEMBL5724558 | Colon cancer organoid | 12 |
| - | 10.6019/CHEMBL4507304 | Epidermal growth factor receptor | 12 |
| - | 10.6019/CHEMBL4507304 | Receptor-type tyrosine-protein kinase FLT3 | 11 |
| - | 10.6019/CHEMBL4689842 | U2OS | 10 |
| - | 10.6019/CHEMBL4507304 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 10 |
| - | 10.6019/CHEMBL4689842 | Fibroblast | 9 |
| - | 10.6019/CHEMBL4507304 | Mast/stem cell growth factor receptor Kit | 9 |
| - | 10.6019/CHEMBL4507304 | Unchecked | 8 |
| - | 10.6019/CHEMBL5608141 | Colon cancer organoid | 6 |
| - | 10.1158/2159-8290.CD-23-0050 | Colon cancer organoid | 5 |
| - | 10.6019/CHEMBL4507304 | Proto-oncogene tyrosine-protein kinase receptor Ret | 4 |
| - | 10.6019/CHEMBL4689842 | HEK-293T | 3 |
| - | 10.6019/CHEMBL4507304 | ALK tyrosine kinase receptor | 3 |
| - | 10.6019/CHEMBL4507304 | Hepatocyte growth factor receptor | 3 |
| - | 10.6019/CHEMBL4507304 | Tyrosine-protein kinase JAK1 | 2 |
| - | 10.6019/CHEMBL4507304 | Ribosomal protein S6 kinase alpha-1 | 2 |
| - | 10.6019/CHEMBL4507304 | Ribosomal protein S6 kinase alpha-4 | 2 |
| - | 10.6019/CHEMBL4507304 | Ribosomal protein S6 kinase alpha-5 | 2 |
Data from ChEMBL 36 via Core Engine