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Compound Detail

CHEMBL4067288

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CC(=O)O[C@H]1[C@@H]2C(=O)c3c(C)cc(O)c4c3[C@@]1(COC4=O)C1=C2c2c(C)cc(O)c3c2[C@@](O)(COC3=O)C1=O

Basic Information

ChEMBL ID CHEMBL4067288
Phase Preclinical
Structure Type MOL
InChI Key RNYVZQRDRWHPNZ-OQLOXQSHSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
7
Publications
0
Known Names

Molecular Properties

532.5
MW (Da)
1.28
ALogP
11
HBA
3
HBD
173.7
PSA (Ų)
0.36
QED
2
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C28H20O11
MW 532.46
Aromatic Rings 2
Heavy Atoms 39
NP-Likeness 1.40

Literature References

PubMed DOI Target Context # Activities
27966935 10.1021/acs.jnatprod.6b00458 Staphylococcus aureus 1
27966935 10.1021/acs.jnatprod.6b00458 Staphylococcus haemolyticus 1
27966935 10.1021/acs.jnatprod.6b00458 Enterococcus faecalis 1
27966935 10.1021/acs.jnatprod.6b00458 Escherichia coli 1
27966935 10.1021/acs.jnatprod.6b00458 HeLa 1
39033406 10.1021/acs.jnatprod.4c00330 B-cell line 1
39033406 10.1021/acs.jnatprod.4c00330 T-cell 1

Data from ChEMBL 36 via Core Engine