Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL4068491

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
Cc1n[nH]c2ccc(-c3cc(NCCCO)cnc3-c3cc(F)ccc3O)cc12
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL4068491
Phase Preclinical
Structure Type MOL
InChI Key BZERMWHEQZQJAB-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

392.4
MW (Da)
4.24
ALogP
5
HBA
4
HBD
94.1
PSA (Ų)
0.37
QED
0
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C22H21FN4O2
MW 392.43
Aromatic Rings 4
Heavy Atoms 29
NP-Likeness -1.01

Literature References

PubMed DOI Target Context # Activities
28714692 10.1021/acs.jmedchem.7b00076 Fibroblast growth factor receptor 2 1
28714692 10.1021/acs.jmedchem.7b00076 Fibroblast growth factor receptor 1 1
28714692 10.1021/acs.jmedchem.7b00076 Fibroblast growth factor receptor 3 1

Data from ChEMBL 36 via Core Engine