Compound Detail
CHEMBL4071167
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4071167 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LQANMLZZZONKCX-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
346.4
MW (Da)
2.71
ALogP
5
HBA
1
HBD
67.9
PSA (Ų)
0.92
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 4.81
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor 2 CHEMBL4016 | EC50 | 4.81 | 4.81 | 15595.5 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor 2 | EC50 | = | 15595.53 | nM | 4.81 | Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expres... | 29256599 |
| Glutamate receptor 2 | EC50 | = | 15600.0 | nM | 4.81 | Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expres... | 29256599 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 29256599 | 10.1021/acs.jmedchem.7b01323 | Glutamate receptor 2 | 2 |
Data from ChEMBL 36 via Core Engine