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Compound Detail

CHEMBL4073992

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CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)Cn2cc(-c3ccc(C(=O)O)cc3)nn2)OC(C(=O)O)=C[C@@H]1N

Basic Information

ChEMBL ID CHEMBL4073992
Phase Preclinical
Structure Type MOL
InChI Key XLWPGZDVROAJSD-SEYFSXTGSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
4
Publications
0
Known Names

Molecular Properties

461.4
MW (Da)
-1.44
ALogP
10
HBA
6
HBD
210.1
PSA (Ų)
0.27
QED
1
Ro5 Violations
8
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C20H23N5O8
MW 461.43
Aromatic Rings 2
Heavy Atoms 33
NP-Likeness -0.02

Literature References

PubMed DOI Target Context # Activities
29425031 10.1021/acs.jmedchem.7b01574 Sialidase-2 1
29425031 10.1021/acs.jmedchem.7b01574 Sialidase-1 1
29425031 10.1021/acs.jmedchem.7b01574 Sialidase-3 1
29425031 10.1021/acs.jmedchem.7b01574 Sialidase-4 1

Data from ChEMBL 36 via Core Engine