Compound Detail
CHEMBL4082631
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Basic Information
| ChEMBL ID | CHEMBL4082631 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LCKMWFBVBATZPO-RBUKOAKNSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
312.5
MW (Da)
6.38
ALogP
1
HBA
0
HBD
9.2
PSA (Ų)
0.59
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.18
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(3) dopamine receptor CHEMBL234 | EC50 | 6.18 | 6.18 | 667.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(3) dopamine receptor | EC50 | = | 667.0 | nM | 6.18 | Agonist activity at recombinant human CB1 receptor expressed in CHO-K1 cells ass... | 28182408 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 28182408 | 10.1021/acs.jmedchem.6b01578 | D(3) dopamine receptor | 1 |
Data from ChEMBL 36 via Core Engine