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Compound Detail

CHEMBL4100109

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Cc1n[nH]c2ccc(-c3cc(NCCO)cnc3-c3cc(F)ccc3O)cc12
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL4100109
Phase Preclinical
Structure Type MOL
InChI Key XBRPPAQWEPQQQL-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

378.4
MW (Da)
3.85
ALogP
5
HBA
4
HBD
94.1
PSA (Ų)
0.42
QED
0
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C21H19FN4O2
MW 378.41
Aromatic Rings 4
Heavy Atoms 28
NP-Likeness -1.08

Literature References

PubMed DOI Target Context # Activities
28714692 10.1021/acs.jmedchem.7b00076 Fibroblast growth factor receptor 2 1
28714692 10.1021/acs.jmedchem.7b00076 Fibroblast growth factor receptor 1 1
28714692 10.1021/acs.jmedchem.7b00076 Fibroblast growth factor receptor 3 1

Data from ChEMBL 36 via Core Engine