Compound Detail
CHEMBL411427
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Basic Information
| ChEMBL ID | CHEMBL411427 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HEVLJVLIRXCCAT-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
457.6
MW (Da)
4.08
ALogP
7
HBA
3
HBD
86.4
PSA (Ų)
0.40
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Respiratory syncytial virus CHEMBL612679 | EC50 | 6.8 | 6.8 | 158.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Respiratory syncytial virus | EC50 | = | 158.49 | nM | 6.8 | Inhibition of RSV by MTT assay | 18254606 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18254606 | 10.1021/jm701284j | Respiratory syncytial virus | 1 |
| 18254606 | 10.1021/jm701284j | NON-PROTEIN TARGET | 1 |
Data from ChEMBL 36 via Core Engine