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Compound Detail

CHEMBL4163061

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CCOC(=O)CC[C@H](NC(=O)c1ccccc1SCc1ccc2nc(OC)c(OC)nc2c1)C(=O)OCC

Basic Information

ChEMBL ID CHEMBL4163061
Phase Preclinical
Structure Type MOL
InChI Key MWQQUWRYXVTPKH-FQEVSTJZSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
14
Publications
0
Known Names

Molecular Properties

541.6
MW (Da)
3.94
ALogP
10
HBA
1
HBD
125.9
PSA (Ų)
0.25
QED
1
Ro5 Violations
13
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C27H31N3O7S
MW 541.63
Aromatic Rings 3
Heavy Atoms 38
NP-Likeness -0.99

Literature References

PubMed DOI Target Context # Activities
29339251 10.1016/j.ejmech.2017.12.083 MT4 1
29339251 10.1016/j.ejmech.2017.12.083 Human immunodeficiency virus 1 1
29339251 10.1016/j.ejmech.2017.12.083 Unchecked 1
29339251 10.1016/j.ejmech.2017.12.083 Bovine viral diarrhea virus 1 1
29339251 10.1016/j.ejmech.2017.12.083 BHK-21 1
29339251 10.1016/j.ejmech.2017.12.083 Yellow fever virus 1
29339251 10.1016/j.ejmech.2017.12.083 Mammalian orthoreovirus 1 1
29339251 10.1016/j.ejmech.2017.12.083 Vero 76 1
29339251 10.1016/j.ejmech.2017.12.083 Coxsackievirus B5 1
29339251 10.1016/j.ejmech.2017.12.083 Human poliovirus 1 strain Sabin 1
29339251 10.1016/j.ejmech.2017.12.083 Human orthopneumovirus 1
29339251 10.1016/j.ejmech.2017.12.083 Vesicular stomatitis Indiana virus 1
29339251 10.1016/j.ejmech.2017.12.083 Vaccinia virus 1
29339251 10.1016/j.ejmech.2017.12.083 Human alphaherpesvirus 1 1

Data from ChEMBL 36 via Core Engine