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Compound Detail

CHEMBL4171298

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CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(N)=O

Basic Information

ChEMBL ID CHEMBL4171298
Phase Preclinical
Structure Type MOL
InChI Key WGTOOEXDVIYZPQ-VJBGVNKVSA-N
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

809.0
MW (Da)
-1.27
ALogP
10
HBA
8
HBD
279.4
PSA (Ų)
0.08
QED
2
Ro5 Violations
18
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C40H60N10O8
MW 808.98
Aromatic Rings 2
Heavy Atoms 58
NP-Likeness -0.06

Activity Summary

IC50 1 meas.

Literature References

PubMed DOI Target Context # Activities
28810191 10.1016/j.ejmech.2017.08.019 Peritoneal macrophage 3
28810191 10.1016/j.ejmech.2017.08.019 Erythrocyte 1
28810191 10.1016/j.ejmech.2017.08.019 Angiotensin-converting enzyme 1

Data from ChEMBL 36 via Core Engine