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Compound Detail

CHEMBL4174527

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C=C1[C@H](OC(C)=O)[C@@H](O)[C@@H](OC(C)=O)C(C)(C)/C=C/[C@@H](C)C(=O)[C@@]2(OC(C)=O)C[C@@](C)(OC(C)=O)[C@H](OC(C)=O)[C@@H]2[C@H]1OC(C)=O

Basic Information

ChEMBL ID CHEMBL4174527
Phase Preclinical
Structure Type MOL
InChI Key UFLYYPBSJUQZFA-YHZWSDRVSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
4
Publications
0
Known Names

Molecular Properties

652.7
MW (Da)
2.08
ALogP
14
HBA
1
HBD
195.1
PSA (Ų)
0.25
QED
2
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C32H44O14
MW 652.69
Aromatic Rings 0
Heavy Atoms 46
NP-Likeness 2.34

Literature References

PubMed DOI Target Context # Activities
28925702 10.1021/acs.jnatprod.7b00113 Human immunodeficiency virus 1
28925702 10.1021/acs.jnatprod.7b00113 MT2 1
28925702 10.1021/acs.jnatprod.7b00113 Chikungunya virus 1
28925702 10.1021/acs.jnatprod.7b00113 Vero 1

Data from ChEMBL 36 via Core Engine