Compound Detail
CHEMBL4174924
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Basic Information
| ChEMBL ID | CHEMBL4174924 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OJCLWOIWNFFVCE-OAHLLOKOSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
381.4
MW (Da)
1.12
ALogP
8
HBA
1
HBD
105.8
PSA (Ų)
0.73
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dipeptidyl peptidase 4 CHEMBL284 | IC50 | 7.82 | 7.82 | 15.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dipeptidyl peptidase 4 | IC50 | = | 15.3 | nM | 7.82 | Inhibition of human DPP4 using Gly-Pro-AMC as substrate preincubated for 10 mins... | 29078995 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 29078995 | 10.1016/j.ejmech.2017.10.029 | Dipeptidyl peptidase 4 | 1 |
Data from ChEMBL 36 via Core Engine