Compound Detail
CHEMBL418746
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Basic Information
| ChEMBL ID | CHEMBL418746 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AAKDPDFZMNYDLR-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
177.2
MW (Da)
-2.62
ALogP
5
HBA
4
HBD
84.2
PSA (Ų)
0.35
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 4.27
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Lysosomal alpha-glucosidase CHEMBL2608 | Ki | 4.27 | 4.27 | 54000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Lysosomal alpha-glucosidase | Ki | = | 54000.0 | nM | 4.27 | Inhibitory potency for brewer's yeast alpha-glucosidase in 0.1 M sodium phosphat... | 10340610 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10340610 | 10.1016/s0960-894x(99)00175-4 | Lysosomal alpha-glucosidase | 2 |
| - | 10.1016/S0960-894X(00)80649-6 | Tissue alpha-L-fucosidase | 1 |
Data from ChEMBL 36 via Core Engine