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Compound Detail

CHEMBL4203723

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CC(C)C(=O)O[C@H]1CC[C@]2(C)[C@H]3CC=C4[C@@H]5[C@@H](C)[C@H](C)CC[C@]5(C(=O)O)CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C

Basic Information

ChEMBL ID CHEMBL4203723
Phase Preclinical
Structure Type MOL
InChI Key SUCDUIUDRWABPW-IBLMHXASSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

526.8
MW (Da)
8.30
ALogP
3
HBA
1
HBD
63.6
PSA (Ų)
0.30
QED
2
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C34H54O4
MW 526.80
Aromatic Rings 0
Heavy Atoms 38
NP-Likeness 2.98

Literature References

PubMed DOI Target Context # Activities
29326018 10.1016/j.bmcl.2017.12.060 Plasmodium falciparum 1
29326018 10.1016/j.bmcl.2017.12.060 Vero 1
29326018 10.1016/j.bmcl.2017.12.060 HepG2 1

Data from ChEMBL 36 via Core Engine