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Compound Detail

CHEMBL4209949

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C/C=C(\C)C(=O)N[C@@H](c1ccccc1)[C@@H](O)C(=O)O[C@H]1C[C@@]2(O)[C@@H](OC(=O)c3ccccc3)[C@@H]3[C@]4(OC(C)=O)CO[C@@H]4C[C@H](O[C@@H]4OC[C@@H](O)[C@H](O)[C@H]4O)[C@@]3(C)C(=O)C(=O)C(=C1C)C2(C)C

Basic Information

ChEMBL ID CHEMBL4209949
Phase Preclinical
Structure Type MOL
InChI Key CPQYBXIJDMJNHB-MKQAHOERSA-N
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

920.0
MW (Da)
1.49
ALogP
17
HBA
6
HBD
271.0
PSA (Ų)
0.08
QED
3
Ro5 Violations
11
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C48H57NO17
MW 919.97
Aromatic Rings 2
Heavy Atoms 66
NP-Likeness 2.12

Activity Summary

IC50 1 meas.

Literature References

PubMed DOI Target Context # Activities
28240909 10.1021/acs.jnatprod.7b00006 Unchecked 1
28240909 10.1021/acs.jnatprod.7b00006 HeLa 1

Data from ChEMBL 36 via Core Engine