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Compound Detail

CHEMBL4210302

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CCC(=O)O[C@@H]1Cc2cc3c(c(O)c2-c2c(O)c4c(c(OC)c21)C(=O)c1c(O)cccc1C4=O)C(=O)O[C@H](C)C3

Basic Information

ChEMBL ID CHEMBL4210302
Phase Preclinical
Structure Type MOL
InChI Key AKYMKELYWCSLHP-BDJLRTHQSA-N
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

544.5
MW (Da)
3.91
ALogP
10
HBA
3
HBD
156.7
PSA (Ų)
0.32
QED
1
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C30H24O10
MW 544.51
Aromatic Rings 3
Heavy Atoms 40
NP-Likeness 1.58

Activity Summary

EC50 3 meas. best 4.52

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
No relevant target
CHEMBL2362975
EC50 4.52 4.52 30000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
No relevant target EC50 = 30000.0 nM 4.52 Antioxidant activity assessed as DPPH radical scavenging activity incubated for ... 30178674

Literature References

PubMed DOI Target Context # Activities
30178674 10.1021/acs.jnatprod.8b00397 No relevant target 3

Data from ChEMBL 36 via Core Engine