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Compound Detail

CHEMBL4212383

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N=C(N)NCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CN)C(N)=O

Basic Information

ChEMBL ID CHEMBL4212383
Phase Preclinical
Structure Type MOL
InChI Key GBWDHKBLRMDDCK-DKTXOJPGSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

1323.6
MW (Da)

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C50H102N34O9
MW 1323.60

Literature References

PubMed DOI Target Context # Activities
29407987 10.1016/j.ejmech.2018.01.045 Proteasome component C5 4
29407987 10.1016/j.ejmech.2018.01.045 Proteasome Macropain subunit 4
29407987 10.1016/j.ejmech.2018.01.045 Proteasome Macropain subunit MB1 4
29407987 10.1016/j.ejmech.2018.01.045 KMS-11 1
29407987 10.1016/j.ejmech.2018.01.045 RPMI-8226 1

Data from ChEMBL 36 via Core Engine