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Compound Detail

CHEMBL4218752

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COC(=O)[C@]12CCC(C)(C)C[C@H]1C1=CC[C@@H]3[C@@]4(C)Cc5cnoc5C(C)(C)[C@@H]4CC[C@@]3(C)[C@]1(C)CC2

Basic Information

ChEMBL ID CHEMBL4218752
Phase Preclinical
Structure Type MOL
InChI Key IWGICSHFGAAQJD-QROXQBBHSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

493.7
MW (Da)
7.66
ALogP
4
HBA
0
HBD
52.3
PSA (Ų)
0.30
QED
1
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C32H47NO3
MW 493.73
Aromatic Rings 1
Heavy Atoms 36
NP-Likeness 2.45

Literature References

PubMed DOI Target Context # Activities
28753294 10.1021/acs.jnatprod.7b00271 Unchecked 1
28753294 10.1021/acs.jnatprod.7b00271 Signal transducer and activator of transcription 3 1
28753294 10.1021/acs.jnatprod.7b00271 Nuclear factor erythroid 2-related factor 2 1

Data from ChEMBL 36 via Core Engine