Compound Detail
CHEMBL4225389
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4225389 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VEZIBLSUFZJVBD-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
231.5
MW (Da)
2.98
ALogP
1
HBA
1
HBD
28.7
PSA (Ų)
0.74
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 3.79
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 3-phosphoinositide-dependent protein kinase 1 CHEMBL2534 | IC50 | 3.79 | 3.79 | 163600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 3-phosphoinositide-dependent protein kinase 1 | IC50 | = | 163600.0 | nM | 3.79 | Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluo... | 29150397 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 29150397 | 10.1016/j.bmcl.2017.10.041 | 3-phosphoinositide-dependent protein kinase 1 | 1 |
Data from ChEMBL 36 via Core Engine