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Compound Detail

CHEMBL4226072

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CCOC(=O)c1c(C(=O)OCC)c(-c2ccc3c(c2)OCO3)c2cc(OC)c(OC)cc2c1O[C@@H]1OC[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O

Basic Information

ChEMBL ID CHEMBL4226072
Phase Preclinical
Structure Type MOL
InChI Key VZOZJXVTZGCMTN-VHISSRMDSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
4
Publications
0
Known Names

Molecular Properties

726.7
MW (Da)
4.14
ALogP
16
HBA
0
HBD
186.9
PSA (Ų)
0.19
QED
2
Ro5 Violations
12
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C36H38O16
MW 726.68
Aromatic Rings 3
Heavy Atoms 52
NP-Likeness 0.73

Literature References

PubMed DOI Target Context # Activities
29656990 10.1016/j.bmc.2018.03.033 HT-29 1
29656990 10.1016/j.bmc.2018.03.033 OVCAR-3 1
29656990 10.1016/j.bmc.2018.03.033 MDA-MB-435 1
29656990 10.1016/j.bmc.2018.03.033 MDA-MB-231 1

Data from ChEMBL 36 via Core Engine