Compound Detail
CHEMBL4247845
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Basic Information
| ChEMBL ID | CHEMBL4247845 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RVQONYJGFBAAAA-KRWDZBQOSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
390.8
MW (Da)
3.00
ALogP
5
HBA
2
HBD
93.7
PSA (Ų)
0.56
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.65
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor gamma CHEMBL235 | EC50 | 4.65 | 4.65 | 22390.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor gamma | EC50 | = | 22390.0 | nM | 4.65 | Agonist activity at PPARgamma in human HepG2 cells assessed as activation of PPR... | 30001846 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30001846 | 10.1016/j.bmc.2018.07.005 | Peroxisome proliferator-activated receptor gamma | 3 |
| 30001846 | 10.1016/j.bmc.2018.07.005 | Unchecked | 1 |
| 30001846 | 10.1016/j.bmc.2018.07.005 | Dipeptidyl peptidase 4 | 1 |
Data from ChEMBL 36 via Core Engine