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Compound Detail

CHEMBL4251375

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Clc1ccc(Nc2nc(NCc3ccco3)c3ccccc3n2)cc1Cl
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL4251375
Phase Preclinical
Structure Type MOL
InChI Key VYZRYKRUOKTFTH-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

385.2
MW (Da)
5.89
ALogP
5
HBA
2
HBD
63.0
PSA (Ų)
0.45
QED
1
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C19H14Cl2N4O
MW 385.25
Aromatic Rings 4
Heavy Atoms 26
NP-Likeness -1.90

Literature References

PubMed DOI Target Context # Activities
30258545 10.1021/acsmedchemlett.8b00296 Son of sevenless homolog 1 2

Data from ChEMBL 36 via Core Engine