Compound Detail
CHEMBL426267
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Basic Information
| ChEMBL ID | CHEMBL426267 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZEFQYTSQDVUMEU-PTYLAXBQSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
237.2
MW (Da)
0.30
ALogP
3
HBA
4
HBD
120.8
PSA (Ų)
0.39
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 2A CHEMBL310 | IC50 | 6.64 | 6.64 | 230.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 2A | IC50 | = | 230.0 | nM | 6.64 | Inhibition of [3H]Glu binding to rat N-methyl-D-aspartic acid receptor 2A | 16107147 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16107147 | 10.1021/jm050174x | Glutamate receptor ionotropic, NMDA 2A | 2 |
Data from ChEMBL 36 via Core Engine