Compound Detail
CHEMBL4278293
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4278293 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DMLMAJXQDPTZCN-ZMJPVWNMSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
9
Publications
0
Known Names
Molecular Properties
308.7
MW (Da)
0.30
ALogP
6
HBA
3
HBD
87.7
PSA (Ų)
0.69
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 4.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| CCRF-CEM CHEMBL382 | IC50 | 4.07 | 4.07 | 86000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| CCRF-CEM | IC50 | = | 86000.0 | nM | 4.07 | Antiproliferative activity against human CEM cells after 72 hrs by Coulter count... | 30098481 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30098481 | 10.1016/j.ejmech.2018.07.062 | Human betaherpesvirus 5 | 2 |
| 30098481 | 10.1016/j.ejmech.2018.07.062 | Human alphaherpesvirus 3 | 2 |
| 30098481 | 10.1016/j.ejmech.2018.07.062 | Unchecked | 2 |
| 30098481 | 10.1016/j.ejmech.2018.07.062 | Human alphaherpesvirus 1 | 2 |
| 30098481 | 10.1016/j.ejmech.2018.07.062 | Vaccinia virus | 1 |
| 30098481 | 10.1016/j.ejmech.2018.07.062 | Human alphaherpesvirus 2 | 1 |
| 30098481 | 10.1016/j.ejmech.2018.07.062 | HeLa | 1 |
| 30098481 | 10.1016/j.ejmech.2018.07.062 | CCRF-CEM | 1 |
| 30098481 | 10.1016/j.ejmech.2018.07.062 | L1210 | 1 |
Data from ChEMBL 36 via Core Engine