Compound Detail
CHEMBL4281133
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Basic Information
| ChEMBL ID | CHEMBL4281133 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PDTJSERAGWOEOZ-KRWDZBQOSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
372.9
MW (Da)
4.77
ALogP
3
HBA
1
HBD
55.8
PSA (Ų)
0.51
QED
0
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 8.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Free fatty acid receptor 1 CHEMBL4422 | EC50 | 8.0 | 8.0 | 10.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Free fatty acid receptor 1 | EC50 | = | 10.0 | nM | 8.0 | Agonist activity at FFA1 (unknown origin) | 30296685 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30296685 | 10.1016/j.ejmech.2018.09.071 | Free fatty acid receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine