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Compound Detail

CHEMBL4289718

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O=C(Nc1ccc(C(F)(F)F)cn1)c1cccc2ccc(CO)nc12
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL4289718
Phase Preclinical
Structure Type MOL
InChI Key XPLKXSHZIBJEBH-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

347.3
MW (Da)
3.39
ALogP
4
HBA
2
HBD
75.1
PSA (Ų)
0.76
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C17H12F3N3O2
MW 347.30
Aromatic Rings 3
Heavy Atoms 25
NP-Likeness -1.44

Literature References

PubMed DOI Target Context # Activities
30108871 10.1039/C7MD00213K Fibroblast growth factor receptor 4 3
32930584 10.1021/acs.jmedchem.0c01019 Fibroblast growth factor receptor 4 1

Data from ChEMBL 36 via Core Engine