Compound Detail
CHEMBL4291559
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL4291559 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NQYRMQARVFBPST-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
268.4
MW (Da)
2.66
ALogP
4
HBA
1
HBD
78.4
PSA (Ų)
0.61
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.42
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cerebellar granule neurone CHEMBL614452 | EC50 | 4.42 | 4.42 | 38060.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cerebellar granule neurone | EC50 | = | 38060.0 | nM | 4.42 | Neuroprotective activity against glutamate-induced excitotoxicity in mouse prima... | 30108699 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30108699 | 10.1039/C6MD00509H | Cerebellar granule neurone | 4 |
Data from ChEMBL 36 via Core Engine