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Compound Detail

CHEMBL4297619

ENARODUSTAT
🧪 Phase III
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🧪 Phase III
O=C(O)CNC(=O)c1c(O)cc(CCc2ccccc2)n2ncnc12
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL4297619
Name ENARODUSTAT
Phase Phase III
Structure Type MOL
InChI Key NALAUGMPMIVAOW-UHFFFAOYSA-N

Known Names

Enarodustat Jtz-951
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
2
Known Names
1
Indications
1
Mechanisms

Molecular Properties

340.3
MW (Da)
1.03
ALogP
6
HBA
3
HBD
116.8
PSA (Ų)
0.62
QED
0
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Achiral
USAN Stem -stat

Extended Properties

Molecular Formula C17H16N4O4
MW 340.34
Aromatic Rings 3
Heavy Atoms 25
NP-Likeness -0.58

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
Egl nine homolog 1 inhibitor INHIBITOR Egl nine homolog 1 ✓ ✓

Indications

Renal Insufficiency, Chronic

Data from ChEMBL 36 via Core Engine