Compound Detail
CHEMBL429762
11BETA,13-DIHYDRO-PARTHENOLIDE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL429762 |
| Name | 11BETA,13-DIHYDRO-PARTHENOLIDE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GSVWPONNFJXHJL-IOCBBESTSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
7
Publications
0
Known Names
Molecular Properties
250.3
MW (Da)
2.84
ALogP
3
HBA
0
HBD
38.8
PSA (Ų)
0.38
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Transcriptional activator Myb CHEMBL2380186 | IC50 | 4.3 | 4.3 | 50003.4 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Transcriptional activator Myb | IC50 | = | 50003.45 | nM | 4.3 | Inhibition of c-Myb-induced mim-1 gene expression in doxycyclin-treated chicken ... | 23501116 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23501116 | 10.1016/j.ejmech.2013.02.018 | Transcriptional activator Myb | 2 |
| 18271521 | 10.1021/jm701318x | Platelet | 1 |
| 1431933 | 10.1021/np50086a003 | NON-PROTEIN TARGET | 1 |
| 14695795 | 10.1021/np030278f | SMMC-7721 | 1 |
| 14695795 | 10.1021/np030278f | NON-PROTEIN TARGET | 1 |
| 23565574 | 10.1021/np300882f | ADMET | 1 |
| 23501116 | 10.1016/j.ejmech.2013.02.018 | ADMET | 1 |
Data from ChEMBL 36 via Core Engine