Compound Detail
CHEMBL4297661
TARLOXOTINIB 🧪 Phase II
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
🧪 Phase II
Cn1cnc([N+](=O)[O-])c1C[N+](C)(C)C/C=C/C(=O)Nc1cc2c(Nc3ccc(Cl)c(Br)c3)ncnc2cn1
Basic Information
| ChEMBL ID | CHEMBL4297661 |
| Name | TARLOXOTINIB |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | MUJMYVFVAWFUJL-SNAWJCMRSA-O |
| Active Moiety | CHEMBL4802235 |
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
3
Known Names
2
Indications
1
Mechanisms
Molecular Properties
601.9
MW (Da)
4.60
ALogP
9
HBA
2
HBD
140.8
PSA (Ų)
0.12
QED
1
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Achiral |
Mechanism of Action
| Mechanism | Action Type | Target | Direct | Efficacy |
|---|---|---|---|---|
| Epidermal growth factor receptor inhibitor | INHIBITOR | Epidermal growth factor receptor | ✓ | ✓ |
Indications
Carcinoma, Non-Small-Cell Lung Carcinoma, Squamous Cell
Data from ChEMBL 36 via Core Engine