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Compound Detail

CHEMBL4298200

LIFILEUCEL
💊 Approved Drug
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💊 Approved Drug
No structure available

Basic Information

ChEMBL ID CHEMBL4298200
Name LIFILEUCEL
Phase Approved
Structure Type NONE
Therapeutic ✓ Yes

Known Names

Amtagvi Autologous tumor infiltrating lymphocytes Lifileucel Ln 145 LN-144 Ln-145
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
0
Publications
6
Known Names
12
Indications
1
Mechanisms

Drug Information

Molecule Type Cell
First Approval 2024
Availability Unknown
Chirality Single Enantiomer

Flags

Black Box Warning
USAN Year 2019

Mechanism of Action

Mechanism Action Type Target Direct Efficacy
Somatic cell supplemental therapy - -

Indications

Melanoma Melanoma Melanoma Breast Neoplasms Carcinoma, Non-Small-Cell Lung Carcinoma, Squamous Cell Endometrial Neoplasms Uterine Cervical Neoplasms Uterine Cervical Neoplasms Liver Neoplasms Mesothelioma Neoplasms

ATC Classification

L01XL11
lifileucel
Level 1: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
Level 2: ANTINEOPLASTIC AGENTS

Drug Warnings

Black Box Warning
General Warning
Country: United States

Data from ChEMBL 36 via Core Engine