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Compound Detail

CHEMBL434202

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CNc1nc(-c2ccc(OC)cc2)nc2ncccc12
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL434202
Phase Preclinical
Structure Type MOL
InChI Key HUIAZOHYRSSOKF-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

266.3
MW (Da)
2.74
ALogP
5
HBA
1
HBD
59.9
PSA (Ų)
0.79
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C15H14N4O
MW 266.30
Aromatic Rings 3
Heavy Atoms 20
NP-Likeness -1.09

Literature References

PubMed DOI Target Context # Activities
12668002 10.1016/s0960-894x(03)00163-x Tyrosine-protein kinase SYK 1
22257213 10.1021/jm201271b Tyrosine-protein kinase SYK 1

Data from ChEMBL 36 via Core Engine