Compound Detail
CHEMBL439723
TRIMETHYLAMMONIUM Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL439723 |
| Name | TRIMETHYLAMMONIUM |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GETQZCLCWQTVFV-UHFFFAOYSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
10
Publications
0
Known Names
Molecular Properties
59.1
MW (Da)
0.18
ALogP
1
HBA
0
HBD
3.2
PSA (Ų)
0.38
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.68
Ki 1 meas.
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Trace amine-associated receptor 5 CHEMBL3784908 | EC50 | 5.68 | 5.68 | 2100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Trace amine-associated receptor 5 | EC50 | = | 2100.0 | nM | 5.68 | Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as increase i... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.6019/CHEMBL4495565 | SARS-CoV-2 | 2 |
| 10866370 | 10.1016/s0960-894x(00)00172-4 | No relevant target | 1 |
| 8246232 | 10.1021/jm00075a019 | No relevant target | 1 |
| 10447950 | 10.1021/jm990093z | Neuronal acetylcholine receptor; alpha4/beta2 | 1 |
| 10447950 | 10.1021/jm990093z | Neuronal acetylcholine receptor subunit alpha-7 | 1 |
| 20637607 | 10.1016/j.bmcl.2010.06.090 | High affinity choline transporter 1 | 1 |
| 24249037 | 10.1007/s11095-013-1232-z | No relevant target | 1 |
| 671451 | 10.1021/jm00204a009 | No relevant target | 1 |
| - | 10.1039/C5MD00490J | Trace amine-associated receptor 5 | 1 |
| - | 10.6019/CHEMBL4495564 | Replicase polyprotein 1ab | 1 |
Data from ChEMBL 36 via Core Engine