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Compound Detail

CHEMBL4436207

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CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)O[C@H]1CO[C@H]2OCC[C@H]21)S(=O)(=O)c1ccc(B(O)O)cc1

Basic Information

ChEMBL ID CHEMBL4436207
Phase Preclinical
Structure Type MOL
InChI Key CGVKYOROKILIOK-HEXNFIEUSA-N
0
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

576.5
MW (Da)

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C27H37BN2O9S
MW 576.48

Activity Summary

Ki 2 meas.

Literature References

PubMed DOI Target Context # Activities
36793428 10.1021/acsmedchemlett.2c00464 No relevant target 3
31050421 10.1021/acs.jmedchem.9b00359 Protease 1
36793428 10.1021/acsmedchemlett.2c00464 Human immunodeficiency virus type 1 protease 1

Data from ChEMBL 36 via Core Engine