Compound Detail
CHEMBL443773
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL443773 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UOHKCPKERRYKBE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
328.4
MW (Da)
3.61
ALogP
3
HBA
1
HBD
54.4
PSA (Ų)
0.75
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| K562 CHEMBL385 | IC50 | 4.57 | 4.57 | 27000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| K562 | IC50 | = | 27000.0 | nM | 4.57 | Antiproliferative activity against human K562 cells after 48 hrs | 19220018 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19220018 | 10.1021/jm801338r | K562 | 1 |
| 19220018 | 10.1021/jm801338r | Tubulin | 1 |
Data from ChEMBL 36 via Core Engine