Compound Detail
CHEMBL4439624
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Basic Information
| ChEMBL ID | CHEMBL4439624 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CJWCYEUAMHZNHR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
384.5
MW (Da)
4.66
ALogP
3
HBA
2
HBD
68.1
PSA (Ų)
0.50
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| A549 CHEMBL392 | IC50 | 6.05 | 6.05 | 894.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| A549 | IC50 | = | 894.3 | nM | 6.05 | Antiproliferative activity against human A549 cells after 72 hrs by MTT assay | 30453248 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30453248 | 10.1016/j.ejmech.2018.11.007 | Lymphokine-activated killer T-cell-originated protein kinase | 1 |
| 30453248 | 10.1016/j.ejmech.2018.11.007 | A549 | 1 |
| 30453248 | 10.1016/j.ejmech.2018.11.007 | HCT-116 | 1 |
| 30453248 | 10.1016/j.ejmech.2018.11.007 | HCT-15 | 1 |
Data from ChEMBL 36 via Core Engine