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Compound Detail

CHEMBL4445176

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Cc1c(C(=O)Nc2ccc(Oc3ncnc4[nH]cc(-c5ccccc5)c34)c(F)c2)c(=O)c2cc(-c3ccccc3)ccc2n1C
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL4445176
Phase Preclinical
Structure Type MOL
InChI Key HKXRMWPAXSJHDP-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

595.6
MW (Da)
7.64
ALogP
6
HBA
2
HBD
101.9
PSA (Ų)
0.21
QED
2
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C36H26FN5O3
MW 595.63
Aromatic Rings 7
Heavy Atoms 45
NP-Likeness -1.02

Literature References

PubMed DOI Target Context # Activities
27379978 10.1021/acs.jmedchem.6b00608 Tyrosine-protein kinase receptor UFO 1

Data from ChEMBL 36 via Core Engine