Compound Detail
CHEMBL4446297
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Basic Information
| ChEMBL ID | CHEMBL4446297 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OQZUXJCULSDFGH-AAMHRNTLSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
20
Publications
0
Known Names
Molecular Properties
324.3
MW (Da)
2.89
ALogP
4
HBA
2
HBD
76.0
PSA (Ų)
0.67
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| KB 3-1 CHEMBL614590 | IC50 | 4.4 | 4.4 | 40100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| KB 3-1 | IC50 | = | 40100.0 | nM | 4.4 | Cytotoxicity against human KB3-1 cells assessed as reduction in cell growth incu... | 31599583 |
Literature References
Data from ChEMBL 36 via Core Engine