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Compound Detail

CHEMBL4451018

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CCCn1nc(O)c(CC(N)C(=O)O)n1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL4451018
Phase Preclinical
Structure Type MOL
InChI Key FGCRXYQHIDORDD-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
7
Publications
0
Known Names

Molecular Properties

214.2
MW (Da)
-0.65
ALogP
6
HBA
3
HBD
114.3
PSA (Ų)
0.60
QED
0
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C8H14N4O3
MW 214.22
Aromatic Rings 1
Heavy Atoms 15
NP-Likeness -0.25

Literature References

PubMed DOI Target Context # Activities
30943028 10.1021/acs.jmedchem.8b01986 Glutamate receptor 1 2
30943028 10.1021/acs.jmedchem.8b01986 Glutamate receptor 4 2
30943028 10.1021/acs.jmedchem.8b01986 Glutamate receptor 2 2
30943028 10.1021/acs.jmedchem.8b01986 Unchecked 1
30943028 10.1021/acs.jmedchem.8b01986 Glutamate receptor ionotropic, AMPA 1
30943028 10.1021/acs.jmedchem.8b01986 Glutamate NMDA receptor 1
30943028 10.1021/acs.jmedchem.8b01986 Glutamate receptor 3 1

Data from ChEMBL 36 via Core Engine