Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL4452605

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)CN2CCOCC2)C(=O)N[C@@H](C[C@H]2CCCc3ccccc32)C(=O)[C@@]2(C)CO2)cc1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL4452605
Phase Preclinical
Structure Type MOL
InChI Key KEJWJZGSUUQLSD-QXSQOYFQSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
6
Publications
0
Known Names

Molecular Properties

634.8
MW (Da)
1.91
ALogP
8
HBA
3
HBD
138.6
PSA (Ų)
0.27
QED
1
Ro5 Violations
14
Rot. Bonds

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C35H46N4O7
MW 634.77
Aromatic Rings 2
Heavy Atoms 46
NP-Likeness -0.32

Literature References

PubMed DOI Target Context # Activities
30657666 10.1021/acs.jmedchem.8b01884 Proteasome Macropain subunit 1
30657666 10.1021/acs.jmedchem.8b01884 Proteasome subunit beta type-10 1
30657666 10.1021/acs.jmedchem.8b01884 Proteasome Macropain subunit MB1 1
30657666 10.1021/acs.jmedchem.8b01884 Proteasome subunit beta type-8 1
30657666 10.1021/acs.jmedchem.8b01884 Proteasome component C5 1
30657666 10.1021/acs.jmedchem.8b01884 Proteasome subunit beta type-9 1

Data from ChEMBL 36 via Core Engine