Compound Detail
CHEMBL4453742
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
O=c1oc2ccccc2cc1-c1nn(C(Nc2ccc(Oc3ccc(NC(c4ccc(Cl)cc4Cl)n4nc(-c5cc6ccccc6oc5=O)oc4=S)cc3)cc2)c2ccc(Cl)cc2Cl)c(=S)o1
Basic Information
| ChEMBL ID | CHEMBL4453742 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CMKYOZFHMOYFFW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
1006.7
MW (Da)
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Alpha glucosidase CHEMBL3833502 | IC50 | 7.16 | 7.16 | 70.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Alpha glucosidase | IC50 | = | 70.0 | nM | 7.16 | Inhibition of alpha-glucosidase (unknown origin) using p-nitro phenyl glucopyran... | 31112894 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 31112894 | 10.1016/j.ejmech.2019.04.025 | Alpha glucosidase | 1 |
Data from ChEMBL 36 via Core Engine