Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL445823

LIRIODENDRIN
Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
COc1cc([C@H]2OC[C@H]3[C@@H]2CO[C@@H]3c2cc(OC)c(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c(OC)c2)cc(OC)c1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

Basic Information

ChEMBL ID CHEMBL445823
Name LIRIODENDRIN
Phase Preclinical
Structure Type MOL
InChI Key FFDULTAFAQRACT-XKBSQSBASA-N
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
12
Publications
0
Known Names

Molecular Properties

742.7
MW (Da)
-1.85
ALogP
18
HBA
8
HBD
254.1
PSA (Ų)
0.12
QED
3
Ro5 Violations
12
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C34H46O18
MW 742.72
Aromatic Rings 2
Heavy Atoms 52
NP-Likeness 1.08

Activity Summary

IC50 1 meas.

Literature References

PubMed DOI Target Context # Activities
1965200 10.1021/np50072a008 NON-PROTEIN TARGET 4
24953601 10.1016/j.bmcl.2014.05.077 RAW264.7 2
28038832 10.1016/j.bmcl.2016.12.028 RAW264.7 2
1965200 10.1021/np50072a008 HT-1080 1
1965200 10.1021/np50072a008 KB 1
1965200 10.1021/np50072a008 P388 1
11473436 10.1021/np000614h NON-PROTEIN TARGET 1
1710653 10.1021/np50073a012 Human immunodeficiency virus type 1 reverse transcriptase 1
18986199 10.1021/np8004166 RAW264.7 1
24953601 10.1016/j.bmcl.2014.05.077 No relevant target 1
28073678 10.1016/j.bmcl.2016.12.075 N9 1
28911817 10.1016/j.bmcl.2017.08.047 BV-2 1

Data from ChEMBL 36 via Core Engine