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Compound Detail

CHEMBL445951

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C[C@H]1[C@@H](CCNC(=O)NCC[C@H]2O[C@@H]3O[C@@]4(C)CC[C@H]5[C@H](C)CC[C@@H]([C@H]2C)[C@@]35OO4)O[C@@H]2O[C@@]3(C)CC[C@H]4[C@H](C)CC[C@@H]1[C@@]24OO3

Basic Information

ChEMBL ID CHEMBL445951
Phase Preclinical
Structure Type MOL
InChI Key HFOFZPOYMRKFOD-SBUWDEJESA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

648.8
MW (Da)
5.57
ALogP
9
HBA
2
HBD
115.0
PSA (Ų)
0.36
QED
2
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C35H56N2O9
MW 648.84
Aromatic Rings 0
Heavy Atoms 46
NP-Likeness 1.32

Literature References

PubMed DOI Target Context # Activities
19136263 10.1016/j.bmc.2008.12.017 HL-60 1
19136263 10.1016/j.bmc.2008.12.017 Plasmodium falciparum 1

Data from ChEMBL 36 via Core Engine