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Compound Detail

CHEMBL4469489

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CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)CSSC[C@@H](C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)[C@@H](C)CC)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCC(=O)O)NC1=O

Basic Information

ChEMBL ID CHEMBL4469489
Phase Preclinical
Structure Type MOL
InChI Key HBJGGMQQUHUSAH-VZUMCMRBSA-N
0
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

1449.7
MW (Da)

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C67H96N14O18S2
MW 1449.72

Activity Summary

Kd 2 meas.

Literature References

PubMed DOI Target Context # Activities
31082234 10.1021/acs.jmedchem.8b02027 Tumor necrosis factor ligand superfamily member 11 2

Data from ChEMBL 36 via Core Engine