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Compound Detail

CHEMBL4476583

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CC(C)[C@H]1CC[C@@](O)(COC(=O)/C(=C/[C@@H]2[C@@H](C(C)C)CC[C@@]3(OC(=O)/C(=C/[C@H]4C=C(CO)CC[C@@H]4C(C)C)CO)COC(=O)[C@@H]23)CO)[C@H]2C(=O)OCC(C(=O)O)=C[C@H]12

Basic Information

ChEMBL ID CHEMBL4476583
Phase Preclinical
Structure Type MOL
InChI Key KFHAQDUENWYFDP-PSZBQQQZSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
11
Publications
0
Known Names

Molecular Properties

815.0
MW (Da)
3.70
ALogP
13
HBA
5
HBD
223.4
PSA (Ų)
0.07
QED
2
Ro5 Violations
14
Rot. Bonds

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C44H62O14
MW 814.97
Aromatic Rings 0
Heavy Atoms 58
NP-Likeness 1.57

Literature References

PubMed DOI Target Context # Activities
31625738 10.1021/acs.jnatprod.9b00760 Staphylococcus aureus 2
31625738 10.1021/acs.jnatprod.9b00760 Escherichia coli 2
31625738 10.1021/acs.jnatprod.9b00760 Pseudomonas aeruginosa 2
31625738 10.1021/acs.jnatprod.9b00760 Klebsiella pneumoniae 2
31625738 10.1021/acs.jnatprod.9b00760 SW-620 1
31625738 10.1021/acs.jnatprod.9b00760 NCI-H460 1
31625738 10.1021/acs.jnatprod.9b00760 Candida albicans 1
31625738 10.1021/acs.jnatprod.9b00760 Bacillus subtilis 1
31625738 10.1021/acs.jnatprod.9b00760 Streptococcus pyogenes 1
31625738 10.1021/acs.jnatprod.9b00760 Acinetobacter baumannii 1
31625738 10.1021/acs.jnatprod.9b00760 Enterococcus faecalis 1

Data from ChEMBL 36 via Core Engine