Compound Detail
CHEMBL448078
COCHINOLIDE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL448078 |
| Name | COCHINOLIDE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BSEKYAJQRZECLG-XLLULAGJSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
258.3
MW (Da)
1.61
ALogP
4
HBA
2
HBD
66.8
PSA (Ų)
0.79
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 4.51
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human alphaherpesvirus 1 CHEMBL377 | EC50 | 4.51 | 4.51 | 31000.0 | 1 |
| Human alphaherpesvirus 2 CHEMBL370 | EC50 | 4.07 | 4.07 | 86000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human alphaherpesvirus 1 | EC50 | = | 31000.0 | nM | 4.51 | Antiviral activity against HSV1 | 15104498 |
| Human alphaherpesvirus 2 | EC50 | = | 86000.0 | nM | 4.07 | Antiviral activity against HSV2 | 15104498 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15104498 | 10.1021/np034052o | Human alphaherpesvirus 1 | 1 |
| 15104498 | 10.1021/np034052o | Human alphaherpesvirus 2 | 1 |
| 15104498 | 10.1021/np034052o | Human immunodeficiency virus 1 | 1 |
| 9584406 | 10.1021/np970341z | Human alphaherpesvirus 1 | 1 |
| 9584406 | 10.1021/np970341z | Human alphaherpesvirus 2 | 1 |
Data from ChEMBL 36 via Core Engine